Nicotinamide (Vitamin B3) (CAS: 98-92-0)

• CAS No.: 98-92-0
• Environmental Protection: Yes
• Color: White
• Model NO.: CAS number 98-92-0
• Classification: Vitamin
• Function: Feed Processing and Preservation Agent
• Appearance: Powder
• CAS Number: 98-92-0
• Molecular Formula: C6h6n2o
• Density: 1.4463G/Cm3
• Einecs: 202-713-4
• Transport Package: 25kg/Bag
• Specification: BP/USP/EP/JP/FCC
• Trademark: Hugestone
• Origin: Jiangsu
• HS Code: 29161900
• Production Capacity: 1000mt/Year

Product Description

Nicotinamide, also known as niacinamide and nicotinic amide, is the amide of nicotinic acid (vitamin B3 / niacin). Nicotinamide is a water-soluble vitamin and is part of the vitamin B group. Nicotinic acid, also known as niacin, is converted to nicotinamide in vivo, and, though the two are identical in their vitamin functions, nicotinamide does not have the same pharmacological and toxic effects of niacin, which occur incidental to niacin's conversion. Thus nicotinamide does not reduce cholesterol or cause flushing, although nicotinamide may be toxic to the liver at doses exceeding 3 g/day for adults. In cells, niacin is incorporated into nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), although the pathways for nicotinic acid amide and nicotinic acid are very similar. NAD+ and NADP+ are coenzymes in a wide variety of enzymatic oxidation-reduction reactions. It's produced by the aqueous aminolysis of 3-cyanopyridine (nicotinonitrile) and subsequent crystallization.

Use in medicine
Skin conditions
Nicotinamide has demonstrated anti-inflammatory actions that may be of benefit to patients with inflammatory skin conditions.These conditions include acne vulgaris, and the compound can suppress antigen-induced, lymphocytic transformation and inhibit 3',5'-cyclic-AMP phosphodiesterase. Nicotinamide has demonstrated the ability to block the inflammatory actions of iodides known to precipitate or exacerbate inflammatory acne.

Anxiety
Studies show that nicotinamide has anxiolytic (anti-anxiety) properties. It may work in a way
.

Food Sources
Nicotinamide occurs in trace amounts mainly in meat, fish, nuts, and mushrooms, as well as to a lesser extent in some vegetables.
 

Items	Specification	Results
Characteristics	White  crystalline  powder	Pass
Assay	99.0~101.0%	99.7%
Heavy  metals	≤   0.001	<   0.001
Related  substances	Complies  with  the  standard	pass
Sulphated  ash	≤   0.02	<   0.02
Melting  point	234~240° C	236.2~237.3° C
Loss  on  drying	<   1.0	0.40
Chloride	≤   0.02	0.07